prepared by Dr. Alper DUNKI Plain radiography remains the first-line and often diagnostic in most bone tumors, while CT provides detailed cortical and 3D anatomical evaluation. MRI offers superior soft-tissue and marrow contrast, essential for assessing intramedullary extension and surgical margins. PET/CT assist in detecting metastases and evaluating treatment response. 1. Introduction 2. Plain Radiography…
prepared by Dr. Hakan ESKARA The WHO introduced the classification of soft tissue and bone tumors (fifth edition) in 2020.The new WHO classification of soft tissue and bone tumors, introduced in 2020 (fifth edition), has made significant improvements in classification and introduced many new diagnoses. Histologic Subtypes of Soft Tissue Sarcomas 1. Undifferentiated Pleomorphic Sarcoma…
Dr. Sefa Giray BATIBAY Musculoskeletal tumours are diverse, historically classified by morphology and histology.WHO classification is the gold standard. Advances in molecular biology, cytogenetics, and sequencing improved diagnostic precision (e.g., EWS-FLI1 in Ewing sarcoma, USP6 rearrangement in ABC). Tissue of Origin Most arise from mesenchymal tissue (bone, cartilage, fibrous tissue, fat, muscle). Some from neuroectodermal cells (nerve sheath tumours, PNET). Others…
