Prepared by Dr. Alper DUNKI Pigmented Villonodular Synovitis (PVNS), also known as tenosynovial giant cell tumor (diffuse type), is a benign but locally aggressive proliferative disorder of the synovium, tendon sheaths, and bursae. It is characterized by hemosiderin deposition, multinucleated giant cells, and synovial villous nodular overgrowth. Although histologically benign, PVNS can cause significant joint…
Prepared by Dr. Alper DUNKI Chondroblastoma is a rare, epiphyseal, benign bone tumor that exhibits locally aggressive behavior.It primarily affects skeletally immature individuals, most commonly males in their second decade of life.Most frequent locations include the distal femur, proximal tibia, proximal humerus, and less commonly the hip or calcaneus. Clinical Presentation Patients typically present with:…
Prepared by Dr. Enes KANAY Non-ossifying fibroma (NOF) is a benign, non-osteogenic bone lesion composed of fibroblastic cells, typically located in the metaphysis of long bones during childhood and adolescence.It is usually asymptomatic and detected incidentally on radiographs obtained for other reasons. 1.Synonyms 2. Associated Conditions / Syndromes NOF can be an isolated finding but…
Prepared by Dr. Erhan OKAY Fibrous dysplasia (FD) is a benign bone disorder characterized by the replacement of normal bone with fibro-osseous tissue, leading to pain, deformity, and fractures. It results from post-zygotic GNAS gene mutations that disrupt osteoblastic differentiation. FD may be monostotic (single bone) or polyostotic, the latter often occurring as part of…
Prepared by Dr. Ahmet Mucteba YILDIRIM GCBT is an aggressive benign bone tumour, classified as intermediate (locally aggressive) in the 2020 WHO classification.Accounts for 5–10% of all primary bone tumours.Typically affects individuals aged 20–40 years.Female > Male (1.3–2:1).Associated conditions: Noonan syndrome, Paget’s disease. Common Sites Clinical Presentation Imaging Features X-ray: CT: MRI: Campanacci Classification Used…
Prepared by Dr. Osman Emre AYCAN Aneurysmal bone cyst (ABC) is a benign but locally aggressive, expansile osteolytic lesion composed of blood-filled cavities separated by fibrous septa. It primarily affects children and young adults, typically in the first two decades of life, with no clear sex predilection. Although non-malignant, it can cause significant pain, swelling,…
Prepared by Dr. Enes KANAY Unicameral bone cyst (UBC) is a benign, fluid-filled intramedullary lesion typically located in the metaphysis or diaphysis of long bones in children and adolescents. It is usually unilocular and adjacent to the cortex. Pathological fracture is the most common presentation. 1.Associated Conditions UBC may coexist with other lesions: 2. Epidemiology…
Prepared by Dr. Ahmet Müçteba YILDIRIM Overview• Enchondroma is a benign hyaline cartilage tumor, accounting for 20-25% of benign bone tumors.• It arises from residual cartilage cells that fail to undergo necrosis after physeal growth.• Can be solitary or multiple (Ollier’s disease, Maffucci syndrome). Clinical Presentation Radiographic Features Enchondromas are typically incidental, well-defined intramedullary lesions…
Prepared by Dr. H. Bilgehan CEVIK · Benign hamartomatous cartilaginous lesions derived from aberrant cartilage through the perichondral ring that may be in the form of solitary or associated with genetic conditions like Multiple Hereditary Exostosis (MHE)· They grow and mature according to typical enchondral ossification and do not occur in bones formed through membranous…
