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Coagulopathies and Venous Thromboembolic Diseases

Prepared by Dr. Alper DUNKI Spot Knowledge   Coagulation Basics Coagulation Mechanisms The coagulation cascade leads to fibrin formation through enzymatic reactions. Fibrin traps platelets, stopping bleeding. Hemophilia A hereditary factor deficiency causing bleeding disorders. Recurrent hemarthroses lead to joint destruction. Von Willebrand Disease A genetic coagulopathy due to vWF deficiency. Trauma- and Surgery-Related Coagulopathies Can…

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Anticoagulants

Prepared by Dr. Alper DUNKI Anticoagulants are medications that prevent clot formation. They are essential in orthopaedics for thromboprophylaxis, especially after surgery. Common Anticoagulants in Orthopaedics: Indications in Orthopaedics: Key Considerations: Contraindications: Bridging and Reversal:

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Musculoskeletal Infections and Microbiology

Prepared by Dr. Alper DUNKI Spot Knowledge Epidemiology & Microbiology Pathogenesis Clinical Findings Diagnosis Treatment Antibiotic Prophylaxis in Orthopaedics Prevention of Surgical Site Infection Periprosthetic Joint Infection Atypical & Rare Infections References